tert-butyl 4-[(1-methylethyl)amino]piperidine-1-carboxylate - Names and Identifiers
Name | 1-Boc-4-Isopropylaminopiperidine
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Synonyms | 1-BOC-4-ISOPROPYLAMINOPIPERIDINE 1-Boc-4-Isopropylaminopiperidine N-Boc-4-iso-propylaMinopiperidine 4-ISO-PROPYLAMINO-1-BOC-PIPERIDINE Acetamide,2,2,2-trifluoro-N-(7-hydroxyethyl)- tert-Butyl 4-(isopropylamino)piperidine-1-carboxylate tert-butyl 4-(isopropylamino)piperidine-1-carboxylate tert-butyl 4-[(1-methylethyl)amino]piperidine-1-carboxylate 4-ISOPROPYLAMINO-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER 4-Isopropylamino-piperidine-1-carboxylic acid tert-butyl ester534595-51-2 1-Piperidinecarboxylicacid, 4-[(1-Methylethyl)aMino]-, 1,1-diMethylethyl ester 1-piperidinecarboxylic acid, 4-[(1-methylethyl)amino]-, 1,1-dimethylethyl ester
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CAS | 534595-51-2
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InChI | InChI=1/C13H26N2O2/c1-10(2)14-11-6-8-15(9-7-11)12(16)17-13(3,4)5/h10-11,14H,6-9H2,1-5H3 |
tert-butyl 4-[(1-methylethyl)amino]piperidine-1-carboxylate - Physico-chemical Properties
Molecular Formula | C13H26N2O2
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Molar Mass | 242.36 |
Density | 0.99±0.1 g/cm3(Predicted) |
Boling Point | 317.6±35.0 °C(Predicted) |
Flash Point | 145.9°C |
Vapor Presure | 0.000381mmHg at 25°C |
pKa | 10.19±0.20(Predicted) |
Storage Condition | Sealed in dry,Room Temperature |
Refractive Index | 1.482 |
tert-butyl 4-[(1-methylethyl)amino]piperidine-1-carboxylate - Introduction
It is an organic compound. Its structure contains a piperidine ring and an isopropylamine group, as well as an N-tert-butoxycarbonyl (Boc) protecting group.
Nature:
is a solid with a white to light yellow color. It is insoluble in water at room temperature, but soluble in some organic solvents, such as methanol, ether and dichloromethane.
Use:
is an important intermediate, widely used in organic synthesis. It can be used as a starting material for the synthesis of a variety of bioactive compounds, including drugs, pesticides and functional molecules.
Preparation Method:
The preparation method of the salt can be obtained by reacting 4-isopropylamine piperidine with tert-butoxycarbonyl chlorinating agent. After completion of the reaction, purification can be performed by a method such as crystallization or column chromatography.
Safety Information:
It is relatively safe under correct handling and storage. However, as with other chemicals, operators should take appropriate safety measures, such as wearing protective glasses and gloves, and work in a well-ventilated laboratory. In addition, they should be kept away from fire sources and oxidizers to prevent hazards such as fire and explosion. When handling the compound, care should be taken to observe the relevant safety practices. In case of any accident or discomfort, seek medical help immediately.
Last Update:2024-04-09 20:52:54